Mild thyroid dysfunction affects one in five women with a history of miscarriage or subfertility
Detecting thyroid abnormalities prior to conception may improve pregnancy outcomes

Date:
June 17, 2020
Source:
The Endocrine Society
Summary:
Mild thyroid abnormalities affect up to one in five women with a
history of miscarriage or subfertility which is a prolonged time
span of trying to become pregnant.



FULL STORY ==========================================================================
Mild thyroid abnormalities affect up to one in five women with a history
of miscarriage or subfertility which is a prolonged time span of trying
to become pregnant, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.


========================================================================== Thyroid disorders are common in women of reproductive age. Although the prevalence of thyroid disorders in pregnancy are well understood, little
is known about how common these disorders are in women prior to pregnancy.

Detecting thyroid disorders before a woman becomes pregnant is essential because thyroid abnormalities can have negative effects such as reduced fertility, miscarriage and pre-term birth.

"This study has found that mild thyroid abnormalities affect up to one
in five women who have a history of miscarriage or subfertility and are
trying for a pregnancy," said Rima Dhillon-Smith, M.B.Ch.B., Ph.D., of
the University of Birmingham and the Birmingham Women's and Children's
NHS Foundation Trust in Birmingham, U.K. "It is important to establish
whether treatment of mild thyroid abnormalities can improve pregnancy
outcomes, given the high proportion of women who could potentially be affected." This study was conducted across 49 hospitals in the U.K. over
five years. The researchers studied over 19,000 women with a history of miscarriage or subfertility who were tested for thyroid function. They
found up to one in five women had mild thyroid dysfunction, especially
those with an elevated BMI and of Asian ethnicity, but overt thyroid
disease was rare. Women who suffered multiple miscarriages were no more
likely to have thyroid abnormalities compared to women who have conceived naturally with a history of one miscarriage.


========================================================================== Story Source: Materials provided by The_Endocrine_Society. Note: Content
may be edited for style and length.


========================================================================== Journal Reference:
1. Arri Coomarasamy, Kristien Boelaert, Shiao Chan, Shakila
Thangaratinam,
Jane Daniels, Mark D Kilby, Martyn Underwood, Rachel Small,
Andrew Sizer, Jackie Ross, Lynne Robinson, Nick Raine-Fenning,
Raj Rai, Siobhan Quenby, Caroline Overton, Natalie Nunes, Khashia
Mulbagal, Yacoub Khalaf, Davor Jurkovic, Pratima Gupta, Tarek
Ghobara, Ayman Ewies, Edmond Edi-Osagie, Justin J Chu, Kalsang
Bhatia, Rina Agrawal, Ruth Bender-Atik, Samantha Farrell-Carver,
Krystyna Baker, Kirandeep K Sunner, Lee J Middleton, Paul P Smith,
Aurelio Tobias, Rima K Dhillon-Smith. The prevalence of thyroid
dysfunction and autoimmunity in women with history of miscarriage
or subfertility. The Journal of Clinical Endocrinology & Metabolism,
2020; DOI: 10.1210/clinem/dgaa302 ==========================================================================

Link to news story: https://www.sciencedaily.com/releases/2020/06/200617091009.htm

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