Lithium in drinking water linked with lower suicide rates

Date:
July 27, 2020
Source:
University of Sussex
Summary:
Naturally occurring lithium in public drinking water may have an
anti- suicidal effect - according to a new study. The study collated
research from around the world and found that geographical areas
with relatively high levels or concentration of lithium in public
drinking water had correspondingly lower suicide rates.



FULL STORY ========================================================================== Naturally occurring lithium in public drinking water may have an
anti-suicidal effect -- according to a new study from Brighton and Sussex Medical School (BSMS) and the Institute of Psychiatry, Psychology & Neuroscience at King's College London.


========================================================================== Published in the British Journal of Psychiatry, the study collated
research from around the world and found that geographical areas with relatively high levels or concentration of lithium in public drinking
water had correspondingly lower suicide rates.

Professor Anjum Memon, Chair in Epidemiology and Public Health Medicine
at BSMS and lead author of the study, said: "It is promising that higher
levels of trace lithium in drinking water may exert an anti-suicidal
effect and have the potential to improve community mental health. The prevalence of mental health conditions and national suicide rates are increasing in many countries.

Worldwide, over 800,000 people die by suicide every year, and suicide is
the leading cause of death among persons aged 15-24 years." "In these unprecedented times of COVID-19 pandemic and the consequent increase
in the incidence of mental health conditions, accessing ways to improve community mental health and reduce the incidence of anxiety, depression
and suicide is ever more important." Lithium, sometimes referred to
as the 'Magic Ion', is widely and effectively used as a medication
for the treatment and prevention of manic and depressive episodes,
stabilising mood and reducing the risk of suicide in people with mood disorders. Its anti-aggressive properties can help reduce impulsivity, aggression, violent criminal behaviour and chronic substance abuse.

Lithium is a naturally occurring element and is found in variable amounts
in vegetables, grains, spices and drinking water. It is present in trace amounts in virtually all rocks, and is mobilised by weathering into soils, ground and standing water, and thus into the public water supply.

The health benefits and curative powers of naturally occurring lithium in
water have been known for centuries. The Lithia Springs, an ancient Native American sacred medicinal spring, with its natural lithium-enriched water,
is renowned for its health-giving properties. In fact, the popular soft
drink 7-Up contained lithium when it was created in 1929.

Recent studies have also linked lithium to reduced incidence of
Alzheimer's disease and other dementias. This raises the potential for
its preventative use to combat the risk of dementia.

Professor Allan Young, Chair of Mood Disorders at King's College London,
said: "This synthesis and analysis of all available evidence confirms
previous findings of some individual studies and shows a significant relationship between higher lithium levels in drinking water and lower
suicide rates in the community. The levels of lithium in drinking water
are far lower than those recommended when lithium is used as medicine
although the duration of exposure may be far longer, potentially
starting at conception. These findings are also consistent with the
finding in clinical trials that lithium reduces suicide and related
behaviours in people with a mood disorder." Professor Memon added:
"Next steps might include testing this hypothesis by randomised community trials of lithium supplementation of the water supply, particularly in communities (or settings) with demonstrated high prevalence of mental
health conditions, violent criminal behaviour, chronic substance abuse
and risk of suicide. This may provide further evidence to support the hypothesis that lithium could be used at the community level to reduce
or combat the risk of these conditions." Professor Carmine Pariante
from the Royal College of Psychiatrists, commented: "This study shows
that the boundaries between medication and nutritional interventions
are not as rigid as we used to think, opening up the possibility of
new treatments that span both domains. More knowledge of the beneficial properties of lithium and its role in regulating brain function can lead
to a deeper understanding of mental illness and improve the wellbeing of patients with depression and other mental health problems." The study
involved systematic review and meta-analysis of all previous studies
on the subject -- conducted in Austria, Greece, Italy, Lithuania, UK,
Japan and USA -- which correlated naturally occurring lithium levels in drinking water samples and suicide rates in 1,286 regions/counties/cities
in these countries.


========================================================================== Story Source: Materials provided by University_of_Sussex. Note: Content
may be edited for style and length.


========================================================================== Journal Reference:
1. Anjum Memon, Imogen Rogers, Sophie M. D. D. Fitzsimmons, Ben Carter,
Rebecca Strawbridge, Diego Hidalgo-Mazzei, Allan
H. Young. Association between naturally occurring lithium
in drinking water and suicide rates: systematic review and
meta-analysis of ecological studies. The British Journal of
Psychiatry, 2020; 1 DOI: 10.1192/bjp.2020.128 ==========================================================================

Link to news story: https://www.sciencedaily.com/releases/2020/07/200727145824.htm

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